In May, the Michigan Value Collaborative (MVC) hosted a virtual sepsis workgroup featuring a presentation on the evolution of Michigan Medicine’s enterprise-wide sepsis initiative and the lessons learned while building a sustainable, multidisciplinary sepsis program. The MVC Coordinating Center hosts workgroup presentations once or twice per month, covering a variety of topics including post-discharge follow-up, sepsis, cardiac rehabilitation, rural health, preoperative testing, and health in action.
Sepsis Workgroup – Michigan Medicine
Sepsis remains one of the leading drivers of mortality across healthcare systems, including Michigan Medicine. When sepsis can be treated, this not only reduces patient mortality, but also length of stay, readmissions, morbidities, and overall health of patients, so it comes as no surprise that Michigan Medicine recognized the need to make modifications to their current approach to sepsis management. Presenter Tami Garcia, MSN, RN, Sepsis Team Manager at Michigan Medicine explained how they began by moving away from siloed approaches to care. Early efforts focused on understanding existing workflows across Michigan Medicine’s enterprise and identifying inconsistencies in sepsis care. This included the recognition, escalation, and treatment of sepsis across adult, maternal, emergency and inpatient care settings.
While the team had a foundation set up with dashboards and procedural guides for screening, there had never been a team dedicated to ensuring consistent sepsis care across the system. Rather than immediately deploy new tools or mandates, this new team prioritized “Gemba walking” to meet providers where they work to better understand barriers, workflows, and frontline realities. As Garcia explained, “we need to build changes with our staff, not to our staff.” Garcia credited this approach to helping the sepsis team identify opportunities to standardize care while also building trust with bedside clinicians.
Building Trust as a Quality Improvement Strategy
A major theme throughout Garcia’s presentation was the importance of developing trust in quality improvement work. She emphasized that credibility and relationships became foundational to the success of this sepsis initiative. In addition to Gemba walking, the team focused on:
- Maintaining a visible unit presence
- Responding quickly to staff concerns
- Closing communication loops
- Listening to frontline staff frustrations
- Incorporating clinician feedback into workflow design
Figure 1. Michigan Medicine’s Sepsis Team Standard Work and Governance Framework
One notable outcome of this approach involved the reduction in excessive Epic alerts that historically contributed to alarm fatigue among nursing staff. Rather than dismissing the concerns, the team partnered with clinicians and informatics specialists to reduce unnecessary alerts and improve usability. This example is related to just one of the four main lessons learned by the sepsis team:
- Trust-building is a deliverable
- Tools must fit a workflow, otherwise they become workarounds
- Sustainment requires ownership
- Reducing burden (e.g., alarms) is improvement, not compromise
Standardizing Sepsis Recognition and Response
Following this period of learning and trust-building, the Michigan Medicine sepsis team began implementing a series of targeted interventions designed to improve reliability and timeliness of care.
Some key initiatives included:
- Re-establishing multidisciplinary sepsis huddles in the adult emergency department
- Enhancing Epic tools and workflows (adult, pediatric, etc.)
- Launching maternal sepsis screening and nurse-initiated patient care orders
- Implementing non-invasive fluid responsiveness technology in ICUs
- Establishing nurse sepsis champions and physician ambassador programs
- Creating neonatal sepsis response workflows in the NICU
Figure 2. Michigan Medicine’s ER Workflow and Sepsis Huddle Process Map
Garcia highlighted the adult emergency department sepsis huddles as one of the team’s most impactful initiatives. The huddles bring nurses and providers together immediately after a positive sepsis screen to rapidly determine next steps and initiate treatment plans. This converts concern into coordinated action and normalizes escalation. Combined with streamlined order workflows and decision-support tools, timeliness of care and collaboration between disciplines have been improved.
Measurable Improvements in Sepsis Outcomes
Measurable improvements in both process and outcome measures since the formation of the dedicated sepsis team in 2022 were then reviewed. The reported improvements included:
- Adult emergency department SEP-1 bundle compliance increased from approximately 50% in 2022 to almost 80% in 2026
- Severe sepsis and septic shock mortality rates decreased from 26.2% in 2022 to 20.1% in 2025
- Maternal sepsis screening rates exceeded 90% for OB triage and 78% for inpatient screens
- Pediatric sepsis alert burden was reduced significantly from over 35,000 OPA’s in 2022 to just under 20,000 in 2025
- Reduced the frequency of first antibiotic administration in neonatal populations at >120 minutes from over 40% to under 15% between the beginning and end of 2025
Garcia repeatedly credited frontline teams for these successes, emphasizing that sustained improvement depended on empowering all team members, especially clinicians, rather than relying solely on centralized oversight.
Expanding Frontline Ownership Through Sepsis Champions
One of the most promising developments discussed was the creation of the RN Sepsis Champion Program. Nurses serving as sepsis champions support local reliability, providing peer-to-peer education, reinforcing workflows, and helping to disseminate best practices within their units. Garcia described how this program has expanded rapidly across the Michigan Medicine organization and has already demonstrated improvements to bundle compliance and mortality outcomes in pilot units. Champions are especially important given high turnover rates and shifting operational pressures in healthcare. With monthly meetings, shared educational resources, and ongoing collaboration, champions help maintain momentum and create local ownership of sepsis improvement efforts.
Looking ahead, Michigan Medicine plans to sustain workflows, expand sepsis huddles, and strengthen support for sepsis champions and physician ambassadors. Garcia closed the presentation by reinforcing that successful sepsis improvement, or perhaps any quality improvement initiative, depends on partnership, humility, and continuous learning. As Garcia explained, “We really want to continue to partner with our teams to make sure they understand why we’re here, that they trust we’re here for the best of everybody -them and their patients.”
MVC Sepsis Workgroup: May 21, 2026
MVC welcomes presenters from across Michigan to share their expertise, success stories, initiatives, and solution-focused ideas with MVC members through various best-practice sharing platforms. Please reach out to us by email if you are interested in being a workgroup presenter or submit an online presentation proposal.